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Article
March 1957

Estimation of Exchangeable Water and Potassium by Radioisotope Dilution in Children

Author Affiliations

Upton, N. Y.
Medical Department, Brookhaven National Laboratory.

AMA Am J Dis Child. 1957;93(3):217-222. doi:10.1001/archpedi.1957.02060040219001
Abstract

Most measurements of the total body water in man using dilution techniques have been made using antipyrine or deuterium oxide (D2O) as tracers. In adult subjects, Schloerb and co-workers, using D2O, obtained mean values of 61.8% and 51.9% of the body weight in male and female subjects, respectively.1 Slightly lower values have been reported using antipyrine.2,3 Body-water percentage appears to decrease with advancing years, apparently due to increase of body fat.6 The earlier literature on body-water measurements by desiccation and other methods has been reviewed by Levitt and Gaudino7 and by Pace and associates.8

In children, Friis-Hansen and co-workers4 determined that body water constituted from 53% to 63% of body weight in "hospital normal" children over 6 months of age, regardless of sex. Higher values were obtained in young infants.

Apart from the patient studied by Pace 8 and the

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