The purpose of this paper is to present a simple formula permitting rapid calculation of the following data essential to the performance of an exchange transfusion for an infant, child, or adult: (a) the volume of donor blood needed; (b) the length of time required to perform the exchange transfusion; (c) the number of "unit exchanges" required; (d) the per cent exchange effected.The formula will be presented after a discussion of background material essential to its effective application. Four typical problems are then discussed, followed by a summary. Derivation of the formula and related subjects are given in an appendix.
The Exchange Transfusion
Since 1946 the exchange transfusion has become the accepted method in treatment of erythroblastosis fetalis.1-3 Since 1950 exchange transfusions have been used to treat blood transfusion reactions4 and poisoning when conventional methods have failed. Poisoning by the following substances has been treated successfully
TROSSMAN CM, ALZOFON FE. An Exchange Transfusion Formula. AMA Am J Dis Child. 1959;98(6):694–698. doi:10.1001/archpedi.1959.02070020696004