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January 1960

Aseptic Meningitis Due to ECHO Virus Type 18

Author Affiliations

Buffalo, N.Y.
From the Department of Bacteriology and Immunology and Department of Pediatrics, University of Buffalo School of Medicine.; Laboratory Branch, Communicable Disease Center, U.S. Public Health Service, Department of Health, Education, and Welfare (Dr. Eckert); Dr. Karzon is a Markle Scholar in Medical Science.

AMA Am J Dis Child. 1960;99(1):1-3. doi:10.1001/archpedi.1960.02070030003001

ECHO virus Type 18 has heretofore been etiologically associated with non febrile diarrheal illness in infants less than one year of age.1 This report presents the isolation of ECHO 18 virus from the cerebrospinal fluid (CSF) and stool of a 12-year-old child with aseptic meningitis and offers evidence for the etiologic association of ECHO 18 with aseptic meningitis.

Report of Case  Clinical Findings.—On Aug. 24, 1955, a 12-year-old white boy developed headache, abdominal pain, occasional emesis, and fever ranging to 103 F. Neck pain appeared on the third day of illness. The headache became more severe the following day, and he vomited three times. He was admitted to Children's Hospital, Buffalo, on the sixth day of illness. Five family associates of the patient were well.At the time of hospital admission he appeared lethargic and moderately ill. His temperature was 100.4 F. The pharynx and left tympanic membrane

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