February 1960

Mechanisms of Hypersensitivity, Henry Ford Hospital International Symposium.

Author Affiliations

Edited by Joseph H. Shaffer, M.D.; Gerald A. LoGrippo, M.D., and Merrill W. Chase, Ph.D. Price, $18.50. Pp. 754. Little, Brown & Company, 34 Beacon St., Boston 6, 1959.

AMA Am J Dis Child. 1960;99(2):257-258. doi:10.1001/archpedi.1960.02070030259021

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This volume brings together a remarkably complete authoritative survey of some of the most important phases of immunology as related to medicine. Several papers are presented bearing on each of the following areas of interest:

Heterogeneity of Antibodies

Detection of Antibodies in Human Sera

Effects of Antibody and of Antigen-Antibody Complexes on Intact Cells and Whole Organisms

Permeability Factors

Participation of Complement in Allergic Responses


Delayed-Type Hypersensitivity Reactions

Immunologic Unresponsiveness

Tolerance and Rejection of Tissue

Hormones and Allergic Responses

The Role of Mycobacteria in Allergic Manifestations

Some Factors Modifying the Response to Allergens

From these topics it can be seen that the volume represents a fairly comprehensive review of modern thought in immunology.

The papers in general are excellent, and much original work of the participants at the Conference is presented. Most of them emphasize the basic principles behind reactions of hypersensitivity and details relating to application of these

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