May 1961

Papilledema in Sydenham's Chorea

Author Affiliations

Department of Neurology, University Hospitals, 1300 University Ave. 6.; From the Departments of Neurology and Pediatrics, University of Wisconsin School of Medicine.

Am J Dis Child. 1961;101(5):641-644. doi:10.1001/archpedi.1961.04020060099014

There are numerous reports of papilledema in association with various disease entities either with1,2 or without the presence of increased intracranial pressure.3,4 The association is most frequent with intracranial space occupying lesions such as those produced by brain tumor.5,6 Infection,7,8 trauma,9 heavy metal toxicity,10 and metabolic diseases,11,12 as well as numerous other clinical states have been known for many years to occur with papilledema.13-17 Recently, attention has been redirected to the syndrome of benign intracranial hypertension.18-22

This paper reports the findings on an 8-year-old girl studied at the University of Wisconsin Hospitals who had classical physical findings of Sydenham's chorea and papilledema. A search of the world medical literature reveals a marked paucity of reports dealing with the simultaneous occurrence of these conditions.

Report of Case  The patient is an 8-year-old white girl who was admitted to the University Hospitals on

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