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February 1963

Hypocaloric Dwarfism and Hydronephrosis in Diabetes Insipidus

Author Affiliations

N. B. Talbot, M.D., Massachusetts General Hospital, Fruit St., Boston 14, Mass.; From the Department of Pediatrics, Harvard Medical School, and the Children's Service, Massachusetts General Hospital.

Am J Dis Child. 1963;105(2):175-181. doi:10.1001/archpedi.1963.02080040177008

In the treatment of diabetes insipidus one may be inclined to focus attention upon polyuria and polydipsia and to be gratified if these appear to be under passably satisfactory control.

Observations to be presented suggest that it may be important also to make sure that some of the secondary effects of polyuria and polydipsia, such as stunting of growth and hydronephrosis, are being prevented and that the time occupied by the disease and its therapy are minimized.

Observations  Case 1.—A 3-year-old male child, when first seen in 1951, had a history of polyuria and polydipsia since the age of 23 months. Closer questioning revealed that 3 weeks before the onset of the symptoms the patient had been knocked down by an older boy. He was drowsy for 24 hours after the fall and had bleeding from the left ear canal. This suggested that skull fracture with severance of the pituitary

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