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Case 1.—A 13-year-old boy developed a purulent otitis media and was given 29 tablets of 0.5 gm of Retasulfin over a period of ten days. On the fourth day thereafter he developed a morbilliform rash and was referred to the clinic. The next day numerous vesicles filled with serous fluid appeared on the skin. These became confluent over a large area and broke when rubbed, leaving a raw surface denuded of epidermis. Three days later the boy's entire body was nearly completely denuded of epidermis. At this time he developed purulent conjunctivitis, an ulcerated inflammation of the oral membranes, purulent exudate of the urethra, and pneumonia. The boy was given antibiotics, prednisone, methandrostenolone (Dianabol), and blood transfusions. The boy survived, and after 35 days of hospitalization he went home in a good state.
Case 2.—A 2½-year-old boy developed acute bronchitis for which he was given an unknown dose of Retasulfin.
BOGDANOWICZ J, AFEK-KAMINSKA M. Report of Three Cases. Am J Dis Child. 1963;106(4):423-424. doi:10.1001/archpedi.1963.02080050425016