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April 1964

Lead Neuropathy In Childhood

Author Affiliations

John M. Freeman, MD, Department of Neurology, 710 W 168th St, New York, NY 10032.; Trainee Fellow (Dr. Freeman), United States Public Health Service grant BT810.; From the Departments of Pediatrics and Neurology (Division of Pediatric Neurology), Columbia Presbyterian Medical Center.

Am J Dis Child. 1964;107(4):337-342. doi:10.1001/archpedi.1964.02080060339003

The major complications of lead ingestion are lead encephalopathy and lead neuropathy. encephalopathy is well known to pediatricians and is the most common conseconsequencquencetoxication in chiin childhood.

Lead neuropathy, while more common than encephalopathy in adults, is rare in childhood. Oly nine cases off lead neufopathychildren have been reported in detail in the Englislish languageterature. Thirtyo-e other cases have been mentioned. The scarcity of detailed reports of this condition, plus the fact that early recognition of neuneu rropathyrevent the even more serious sequel of encephalopathy, has prompted this report.

Report of a Case  A 3½-year-old Neurowith anemia and wepre-ss of two months' duration. Family history was negative foFamily history loginegative forlneuro-isease. Thehematologic disea ment had been normal, -nd previously he hadl, and free of significant disease. He had exhibited pica for almost two years, and had chewed several holes in the plaster of his apartment.He had been well

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