LITTLE REFERENCE has been made to the size of the breast of the newborn except that hyperplasia, engorgement, and milk secretion is physiologic, and that hyperplasia is seen with equal frequency in mature infants of both sexes. It also has been stated that breast development is rarely seen in premature infants, but a detailed study of the latter point has not been presented.*1
In this study, the relationship between the size of the breast nodule and the birth weight and gestation was examined. The data are interpreted to indicate that the presence and size of the breast nodule are, in a general way, correlated with the maturity of the premature infant.
Data were obtained in 196 consecutive premature infants who were born from 1960 through 1962. One hundred and sixteen were white, and the remainder nonwhite, primarily Negro. The observers who evaluated the breast nodules were experienced
KEITEL HG, CHU E. Breast Nodule in Premature Infant. Am J Dis Child. 1965;109(2):121-122. doi:10.1001/archpedi.1965.02090020123005