December 1965

Botryoid Sarcoma (Rhabdomyosarcoma) of the Bile Ducts

Author Affiliations

From the Department of Surgery, Childrens Hospital of Los Angeles, and the University of Southern California, School of Medicine.

Am J Dis Child. 1965;110(6):595-605. doi:10.1001/archpedi.1965.02090030623002

IN THE SECOND edition of Lectures on Pathological Anatomy by Samuel Wilks and Walter Moxon (London, 1875) is found the following:

We recently met with a curious example of a disease. The common duct in a child of four years was dilated to form a cyst as large as the child's head. In the wall of this cyst were crowds of pendulous growths of myomatous structure, in which were embedded numbers of non-striated muscle fibers.1 *

Although the distinction between smooth and striated muscle by microscopic examination had been made prior to this date, the last clause may refer to the gross, rather than the microscopic, appearance of the tumor. In any event, this is a clear description of the autopsy findings in a rhabdomyosarcoma (botryoid sarcoma) of the choledochus. No history is given, but the age is within the range of the proven modern cases. Wilks and Moxon1

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