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June 1967

Plasma Cells in the Circulation in Infants and Children

Author Affiliations

From the Child Research Council, Department of Pediatrics, University of Colorado School of Medicine, Denver.

Am J Dis Child. 1967;113(6):633-638. doi:10.1001/archpedi.1967.02090210047001

THE PURPOSE of this paper is to present the results of plasma cell counts made on the blood of infants and children from birth through adolescence. Of the 628 counts made, over one-half represent brief overlapping longitudinal studies of individual subjects, each of whom was followed up with successive counts over periods of one to five years. The children were all Child Research Council subjects, each of whom was being followed up from the day of birth throughout the life span with many different tests and observations.1 Thus, the variation in a given individual over a time span of his growth, the differences between babies, and the general age trends could all be observed. The first blood sample was taken on the third day. The chief relationships studied were those between the number of plasma cells and (1) the total number of white blood cells, (2) the serum protein

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