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July 1967

Pulmonary Nocardiosis in ChildhoodA Case Report

Author Affiliations

Chapel Hill, NC
From the departments of medicine (Dr. Stites) and pediatrics (Dr. Glezen), School of Medicine, University of North Carolina, Chapel Hill.

Am J Dis Child. 1967;114(1):101-105. doi:10.1001/archpedi.1967.02090220107020

THE OCCURRENCE of Nocardia infections in childhood is rare. Since the late 19th Century when Nocard1 first isolated the organism from cattle and Eppinger2 described the first human case, only 16 cases in children have been documented in the world's literature. Nine cases were diagnosed only at the time of postmortem examination; of the seven cases recognized before death, only four have survived prior to this report.

A comprehensive review of all previously reported Nocardia infections in children was made by Ballenger and Goldring3 in 1957. In the decade since that writing only five additional case reports have appeared. This communication describes the clinical course of successfully treated pulmonary nocardiosis in a 3½-year-old girl in whom the diagnosis was established by direct percutaneous lung biopsy.

Report of a Case  The patient, a 3½-year-old Negro girl, was admitted to the North Carolina Memorial Hospital in September 1965 with

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