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January 1968

Complete Breast Absence in Siblings

Author Affiliations

Brooklyn, NY
From the Department of Pediatrics, State University of New York, Downstate Medical Center, Brooklyn.

Am J Dis Child. 1968;115(1):91-92. doi:10.1001/archpedi.1968.02100010093018

BILATERAL absence of the breast and nipple development in the absence of congenital ectodermal defect or other congenital anomalies is a very rare occurrence. Prior to this century three cases of the isolated anomaly were reported.1-3 Two more recent reports4,5 have been made in which the condition appeared in several members of a family. The subject has been recently reviewed by Trier6 who reported an isolated case. In this report we shall present the case of a brother and sister who exhibited this condition.

Report of Cases  Case 1.—This white girl was born on Feb 2, 1961, the product of a first pregnancy. For most of the gestational period, the mother states that she suffered from nausea and vomiting, for which she took pipamazine tablets (Mornidine), 5 mg twice daily. There were no other prepartum complications, nor was the mother subjected to radiation at this time. Spontaneous

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