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March 1968

Myocardial Hyperbilirubinemia in a Premature Infant

Author Affiliations

Oakland, Calif
From the Department of Pathology, Highland General Hospital, Oakland, Calif.

Am J Dis Child. 1968;115(3):358-361. doi:10.1001/archpedi.1968.02100010360011

BILIRUBIN CRYSTALS have been reported in autopsy tissues of infants who died with high bilirubin levels. These crystals were found especially prevelant in the brain, kidney, and adrenals.1 To the best of our knowledge gross icteric pigmentation with bilirubin crystal deposits in the heart has not been reported.

Pertinent Clinical and Autopsy Findings. The mother is an 18-year-old migratory Mexican, gravida 1, para 1, who had had no prenatal care. The child was born out of wedlock. The expected date of confinement was uncertain. At birth the female child weighed 907.25 gm, at the time of death, seven days later, the baby weighed 880 gm and measured 35 cm, crown to heel. At birth the Apgar score was reported as 2. The patient lived for seven days and during this time frequent apneic spells occurred. On day one, the total bilirubin (TB) was 12.0 mg/100 cc, indirect bilirubin (IB)

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