DOWN'S SYNDROME has been found in all major races,1-11 but there are few quantitative studies of clinical signs on groups other than whites. The occurrence of major malformations in Down's syndrome has been reviewed recently by Warkany, et al.12 A previous report qualitatively discussed the physical findings in a series of 20 Chinese children with Down's syndrome,9 and some quantitative data are available for a series of 11 Japanese cases.5 Quantitative data are available for 29 cases of Oriental origin (Chinese, Japanese, and other) in Hawaii.4
The present article is a study of the frequency of previously described stigmata in a sample of 56 Chinese children with Down's syndrome born in the area of Taipei, Taiwan. It is one phase of a comprehensive investigation of Down's syndrome in Chinese. The other phases, including cytogenetics, dermatoglyphics, and epidemiology, will be reported elsewhere.
Report of Cases
Emanuel I, Huang S, Yeh E. Physical Features of Chinese Children With Down's Syndrome. Am J Dis Child. 1968;115(4):461-468. doi:10.1001/archpedi.1968.02100010463009