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June 1968

Central Nervous System Disease in a Newborn Infant

Author Affiliations

Los Angeles
From the Clinical Pathological Conference, departments of pediatrics (Virology) (Dr. Wright) and pathology (Drs. Reed and Landing), the University of Southern California School of Medicine, and the Childrens Hospital of Los Angeles.

Am J Dis Child. 1968;115(6):739-745. doi:10.1001/archpedi.1968.02100010741019

THE POSSIBLE etiology of central nervous system (CNS) disease in a newborn infant is discussed by three physicians. A representative case is presented. This communication is the result of a clinical conference at the Childrens Hospital of Los Angeles.

Report of a Case  History.—A 10-day-old boy was admitted to the Childrens Hospital of Los Angeles because of a loss of appetite. The infant weighed 2,666 gm (5 lb 14 oz) at birth and was delivered without complications. Tenacious mucus was noted in his oropharynx at birth. The baby was a "poor feeder" and gavage feedings with modified milk food (Similac) were instituted. At 3 days of age he was jaundiced with a total serum bilirubin of 9.3 mg/100 cc. At 1 week of age, the infant weighed 2,467 gm (5 lb 7 oz); he was discharged from the hospital at the insistence of the parents. At home the infant

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