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November 1968

Radiation Reaction in Ataxia Telangiectasia

Author Affiliations

USAF; USAF; USAF, Lackland Air Force Base, Tex
From the departments of pediatrics (Drs. Morgan and Holcomb) and pathology (Dr. Morrissey), Wilford Hall USAF Hospital, Lackland Air Force Base, Tex.

Am J Dis Child. 1968;116(5):557-558. doi:10.1001/archpedi.1968.02100020561022

AN UNTOWARD response to radiotherapy in a patient with ataxia telangiectasia and malignancy was reported recently.1 The present case is reported to provide evidence of a similar experience with a patient who also had this rare disease complex.

Report of a Case  The patient was a 9-year-old white boy who was followed at Wilford Hall USAF Hospital from Oct 5, 1964, until his death on May 1, 1967. He was the product of a full-term gestation and appeared normal during the first year of life. When he started to walk at 15 months of age, ataxia was noted. The child had frequent episodes of bronchitis and ear infections during the first four years of life, and when he was 6 years old, he began having repeated bouts of pneumonia. At age 7, telangiectasia of the auricles and of the palpebral and bulbar conjunctiva became evident, and the diagnosis of

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