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To the Editor.—I have read with great interest the article entitled "Acute Encephalopathy in Children Associated With Hepatocellular Dysfunction" subtitled "Reye's Syndrome Revisited," by Martin Randolph and Nelson Gelfman (Amer J Dis Child 116: 303-307 [Sept] 1968). I am frankly surprised by the use of the eponym for, I believe, it is an inaccuracy to classify this case with those reported in the original or in subsequent articles. Hypoglycorrhachia is a salient feature of this syndrome and, taking exception to Dr. Bradford, too, this is a syndrome.
In the article in question, a cerebrospinal fluid glucose level of 82 was tucked into Table 1 but was not mentioned in the body of the article. A blood glucose level of 110 was noted, to be sure. The child, then, did not have this one important feature of the syndrome as described.
In few areas, reported in the scientific journals, are
WINOGRAD HL. REYE'S SYNDROME. Am J Dis Child. 1968;116(6):688. doi:10.1001/archpedi.1968.02100020692030