[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.147.196.37. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
May 1969

Cystic FibrosisPulmonary Studies in Children, Adolescents, and Young Adults

Author Affiliations

Miami, Fla
From the Department of Pediatrics, University of Miami School of Medicine, Miami, Fla. Dr. Zelkowitz is a fellow of the National Cystic Fibrosis Research Foundation.

Am J Dis Child. 1969;117(5):543-547. doi:10.1001/archpedi.1969.02100030545007
Abstract

THE SURVIVAL of children with cystic fibrosis beyond the newborn period is directly associated with the severity of their pulmonary involvement. In the last decade, the advances in medical care have resulted in the survival of more children with cystic fibrosis into young adulthood.1 This has allowed objective evaluation of the progression of pulmonary involvement in these patients. Cystic fibrosis has been found to be associated with a pattern of airway obstruction,2,3 poor intrapulmonary gas mixing,4,5 increase in residual volume,6,7 loss of lung elasticity,7 and changes in gas diffusion.8

This report is an analysis of the studies of 66 children with cystic fibrosis who have a wide spectrum of pulmonary disease and whose intensity of therapy and years of treatment are variable. Pulmonary function studies were evaluated to determine which tests could be done simply and frequently, yet provide accurate assessments of current pulmonary

First Page Preview View Large
First page PDF preview
First page PDF preview
×