December 1969

Modification of Human MetabolismA Challenge and an Opportunity

Author Affiliations

Bethesda, Md
From the National Institute of Child Health and Human Development, Bethesda, Md.

Am J Dis Child. 1969;118(6):817-823. doi:10.1001/archpedi.1969.02100040819003

THE INVITATION by the president of the Society to present speculations on the future of pediatric research in metabolism is both an opportunity and a challenge. If the pace of scientific accomplishment in understanding metabolic disease during the past 15 years is an indicator of future progress, any speculation we examine briefly today may become an accomplishment much sooner than we expect. I have chosen to examine what our accomplishments might be during a period of three decades because it appears to me that during this period we shall realize the same types of achievement in dealing with metabolic disease as we have realized with the three traditional scourges of infant life: diarrheal disease, nutrition, and respiratory infection.

Although I must poach upon the subject matter of my predecessor, since metabolic manipulation must involve the fetus in utero, I shall steer clear of the assignment of my successor, Dr. Kurt

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