To the Editor.—Dudding et al1 in 1967 reported a family with multiple defects and suggested it be called the oto-palato-digital syndrome. In the sibship described there were three affected male subjects. It was suggested that the entity was probably autosomal recessive but could be X-linked.
Two boys have recently been seen at this clinic with similar anomalies; they are half brothers. The clinical details and roentgenograms were sent to the National Foundation Birth Defects Evaluation Center, Boston, who diagnosed the otopalato-digital syndrome. Their clinical features are identical with those described.
The mother of these two boys is
TURNER G. INHERITANCE OF THE OTO-PALATO-DIGITAL SYNDROME. Am J Dis Child. 1970;119(4):377. doi:10.1001/archpedi.1970.02100050379022