The central nervous system (CNS) has been involved in previously reported cases of anaphylactoid purpura in children. Headache, with or without hypertension, is present in 25% to 40% of cases. There are a number of case reports dealing with convulsions, hemiparesis, or coma in children with Schönlein-Henoch purpura. The majority of these complications are due to hypertensive encephalopathy; a few result from well documented subarachnoid hemorrhages.1 Most of the patients recover completely, although in one fatal case, intracerebral hemorrhage was observed at autopsy.2
Of the children reported in large series, approximately 25% have scalp or facial edema. The present case report describes the course of a 3-year-old girl with anaphylactoid purpura who developed a facial nerve palsy during the course of her illness. There has been no previously reported peripheral nerve involvement in the English literature.
Report of a Case
A 3-year-old white girl was admitted to the
Kaplan JM, Quintana P, Samson J. Facial Nerve Palsy With Anaphylactoid Purpura. Am J Dis Child. 1970;119(5):452-453. doi:10.1001/archpedi.1970.02100050454013