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This book begins with a succinct and perceptive preface by Humphrey which is followed by a readable up-to-date theoretical discussion of antibody responses by Talmage, a section on the intrauterine development of lymphoid tissues and immunoglobulins by Adinolfi and Wood, a chapter on phylogenetic development of antibody structure and function by Clem and Leslie, a presentation of the immunological factors which accompany mammalian fertilization and embryonic development by Billington, a treatise on maternal sensitization by fetal red blood cells, white blood cells, and platelets by McConnell, and a helpful discussion of primary immunological deficiencies by Hobbs.
The reviewer is not in agreement with the practice of classifying dysgammaglobulinemias as to types I to VII which seems both cumbersome and uninformative. It is particularly confusing since different authors use varying designations (eg, the type IV of Hobbs is the same as type III of Rosen and Janeway). The system seems outmoded
HEINER DC. Clinics in Developmental Medicine No. 34, Immunology and Development. Am J Dis Child. 1970;120(3):282-283. doi:10.1001/archpedi.1970.02100080166031