Three cases of primary nonspecific ileal ulceration in children who presented with a similar clinical picture of anemia, acute, and chronic rectal bleeding and exhibited varying types of pathological findings are reported. Although the etiology of these lesions remains obscure, the association of such ulcers with either massive painless rectal bleeding or with chronic hypochromic anemia and melena is emphasized. Exploratory laparotomy, including transillumination of the bowel, was necessary to identify these lesions which were then resected uneventfully and without recurrence.
Grosfeld JL, Schiller M, Weinberger M, Clatworthy HW. Primary Nonspecific Ileal Ulcers in Children. Am J Dis Child. 1970;120(5):447-450. doi:10.1001/archpedi.1970.02100100111012