January 1971

"Arthrogryposis Multiplex Congenita" in One of Identical Twins

Author Affiliations

Syracuse, NY
From the Department of Pediatrics, State University of New York, Upstate Medical Center, State University Hospital, Syracuse, NY. Dr. Pedreira is now in Gaithersburg, Md.

Am J Dis Child. 1971;121(1):64-66. doi:10.1001/archpedi.1971.02100120100016

One monozygotic twin is afflicted with arthrogryposis multiplex congenita. A review of the literature has revealed an apparently inconsistent pattern of transmission, conflicting views as to the primary site of involvement, a wide spectrum of variably associated congenital anomalies, and a postulated link with other identified neurologic disorders. We support the proposal that arthrogryposis is a sign present in several syndromes, probably of differing etiologies. Classification under this purely descriptive term should be avoided.