Radiologic and cine studies in a patient with acute lymphocytic leukemia with dysphagia and chest pain showed presence of filling defects along the distal one third of the esophagus. No signs of portal hypertension were present and the spleen was not enlarged. A leukemic infiltrate of the esophagus was suspected and radiotherapy to the distal one third of the esophagus was instituted. Prompt cessation of the chest paint and dysphagia occurred and the filling defects decreased considerably in size two weeks following the course of radiotherapy.
Al-Rashid RA, Harned RK. Dysphagia Due to Leukemic Involvement of the Esophagus. Am J Dis Child. 1971;121(1):75-76. doi:10.1001/archpedi.1971.02100120111019