During the past ten years clinical experience has indicated that bacterial interference can be useful in curtailing staphylococcal disease among newborn babies in the nursery during epidemics and in patients with chronic furunculosis. Studies in a variety of animal models and in vitro have permitted investigations of mechanisms responsible for this ecologic relationship. However, to date, the explanation of this phenomenon in the human remains unknown.
Shinefield HR, Ribble JC, Boris M. Bacterial Interference Between Strains of Staphylococcus aureus, 1960 to 1970. Am J Dis Child. 1971;121(2):148-152. doi:10.1001/archpedi.1971.02100130102013