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June 1971

Sexual Precocity as the Only Sign of a Brain Tumor in a 9-Year-Old Boy

Author Affiliations

Washington, DC
From the Section of Endocrinology (Drs. Hung and August) and the Department of Neurology and Neurosurgery (Drs. Milhorat and Nelson), Children's Hospital of the District of Columbia, the departments of pediatrics (Drs. Hung and August) and neurology (Dr. Nelson), George Washington University School of Medicine, Washington, DC, and the Department of Surgical Neurology (Dr. Milhorat), National Institute of Neurological Diseases and Stroke, Bethesda, Md.

Am J Dis Child. 1971;121(6):524-527. doi:10.1001/archpedi.1971.02100170106018

Clinical, laboratory, and pathologic observations were made in a 9-year-old boy with sexual precocity and no significant neurological findings. X-ray films of the skull, brain scan, and examination of the cerebrospinal fluid were unremarkable. The correct diagnosis (hypothalamic tumor) was established only by pneumoencephalography. We believe that pneumoencephalography is mandatory in any boy with sexual precocity in whom a specific cause is not evident.