A 10-month-old child with renal-cell carcinoma presented as the youngest reported case with unilateral tumor. Terminally the child showed persisting high fever, elevated serum alkaline phosphatase values, hepatosplenomegaly, abnormal liver function test results, leukemoid reaction, elevated serum haptoglobin level, increase of urinary erythropoietin, marked elevation of plasma renin value, and supernormal levels of several coagulation factors. Autopsy showed no distant metastases and no parenchymal involvement.
Pochedly C, Suwansirikul S, Penzer P. Renal-Cell Carcinoma With Extrarenal Manifestations in a 10-Month-Old Child. Am J Dis Child. 1971;121(6):528-530. doi:10.1001/archpedi.1971.02100170110019