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June 1971


Author Affiliations

Los Angeles

Am J Dis Child. 1971;121(6):543-544. doi:10.1001/archpedi.1971.02100170125025

To the Editor.—The review article in the December issue by Wittig (Amer J Dis Child120:578-582, 1970) which purports to critically summarize the current status of hyposensitization (immunotherapy) in atopic disease, while laudable in certain areas, is confusing and even disturbing in many important respects.

The author appears to generally endorse this mode of therapy providing the physician has determined the patient to be atopic, has identified his allergens, and carefully evaluates therapy as to its safety and efficacy. However, these commendable stipulations are followed in the same breath by such serious indictments concerning possible complications of immunotherapy and doubts about its value, that all but the staunchest advocate might abandon it, if he were to believe the interpretation of the literature made by the author.

The danger of injecting foreign antigens into man requires the most careful scrutiny both in treating allergic disease and in the prophylaxis

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