Nine infants with intractable diarrhea and marasmus were fed intravenously with a crystalline amino acid-hypertonic glucose solution from 14 to 37 days. All recovered their ability to absorb all nutrients and are now normal without evidence of persistent underlying cause for diarrhea from 12 to 28 months later. This new technique represents an important form of therapy for this small but seriously ill group of infants. Two unusual complications of the therapy occurred.
Keating JP, Ternberg JL, Dodge PR. Amino Acid-Hypertonic Glucose Treatment for Intractable Diarrhea in Infants. Am J Dis Child. 1971;122(3):226-228. doi:10.1001/archpedi.1971.02110030084009