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September 1971

Burkitt's Lymphoma.

Author Affiliations


Am J Dis Child. 1971;122(3):275-276. doi:10.1001/archpedi.1971.02110030133028

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Burkitt's lymphoma has assumed an importance far beyond that which would have been called for by its incidence in the world. It has been referred to as the potential Rosetta stone among tumors because of the possibility that clues provided through study of Burkitt's lymphoma may help decipher many of the mysteries about cancer in general. Epidemiological studies have suggested that because of the distribution of this tumor in Africa coinciding with malaria distribution that a vector born agent may be the causative factor. The relationship of this lymphoma to the EB virus (also related to infectious mononucleosis) has provided a further challenge to people interested in viral involvement in the etiology of malignancy. Chemotherapy of the tumor has provided long, apparently tumor-free periods for a small proportion of patients with Burkitt's lymphoma. These observations have raised hopes of learning from their experiences to understand better the use of chemotherapy

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