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December 1971

Renal Function and Drug Action.

Am J Dis Child. 1971;122(6):552. doi:10.1001/archpedi.1971.02110060122027

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In this volume entitled Renal Function and Drug Action the author has suggested in the introduction that he plans to compile information as to how renal function affects drug action, with a particular emphasis on providing a helpful volume for clinicians caring for patients with impaired kidney function. To this end he has succeeded reasonably well. While the subject has not been dealt with in great depth, there is an adequate list of references following each chapter which makes it possible to seek further information on the particular problem under study.

The book is composed of eight chapters concerning the mechanism of drug excretion, drug metabolism in uremia, impaired function, and drug sensitivity, as well as a chapter on anesthesia for uremic patients, and the use of dialysis for drug poisoning and intoxication. The major portion of the book is devoted to the effects of renal insufficiency on the actions

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