March 1972

Inappropriate Antidiuretic Hormone Secretion in a Neonate With Meningitis

Author Affiliations

Birmingham, Ala
From the Perinatal Research Laboratory, Newborn Division, Department of Pediatrics, University of Alabama Medical Center, Birmingham.

Am J Dis Child. 1972;123(3):251-253. doi:10.1001/archpedi.1972.02110090121021

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) was documented in a neonate with bacterial meningitis. Excessive administration of fluids lead to hyponatremia, hyperosmolality of the urine, and inappropriate natruresis which responded to fluid restriction.