August 1972

Failure of Catch-up Growth After Cushing's Syndrome in Childhood

Author Affiliations

Los Angeles
From the departments of pediatrics, University of California, Irvine, University of California, Los Angeles, and the Memorial Hospital Medical Center, Long Beach, Calif. Dr. Mosier is now with the University of California, Irvine. Dr. Schultz is now with the University of Wisconsin Medical Center.

Am J Dis Child. 1972;124(2):251-253. doi:10.1001/archpedi.1972.02110140101015

Failure of catch-up in linear growth was experienced by a girl after total adrenal ectomy for Cushing's syndrome. There is a possible correlation between this and failure of catch-up growth in the cortisone-treated rat. The degree of catch-up growth after hyperadrenocorticism may be related to intensity and duration of glucocorticoid exposure, age of the patient, and individual susceptibility of growth mechanisms to damage by exposure to high levels of glucocorticoids.