August 1972

Arachnodactyly (Marfan's Syndrome) With XYY Karyotype

Author Affiliations

From the University Affiliated Program for the Mentally Retarded, the Department of Pediatrics of the University of Cincinnati, College of Medicine (Dr. Dignan); the Department of Internal Medicine, Metabolism Division, University Medical Center, Cincinnati (Dr. Kreines); and the Children's Hospital Research Foundation (Drs. Soukup and Warkany).

Am J Dis Child. 1972;124(2):266-270. doi:10.1001/archpedi.1972.02110140116017

The chromosome analysis for an unusually tall 13-year-old boy with long slender limbs, clawed toes, pigeon chest, myopia with corectopia, and behavior problems showed a 47, XYY constitution. His dermatoglyphics are characterized by an extremely low ridge count. The diagnosis of Marfan's syndrome is considered.