The oral-hand-foot syndrome caused principally by coxsackievirus A16 and known as hand-foot-and-mouth disease has become a common summer-fall complaint. The appearance and distribution of lesions in the full syndrome is highly characteristic and readily diagnosable to those physicians familiar with it. Fortunately, the infection rarely causes severe or lingering disease. Symptomatic treatment, particularly of the oral lesions, is often helpful in alleviating the associated discomfort.
Tindall JP, Callaway JL. Hand-Foot-and-Mouth Disease—It's More Common Than You Think. Am J Dis Child. 1972;124(3):372-375. doi:10.1001/archpedi.1972.02110150070013