Aminoglutethimide, an anticonvulsive agent, may have been the causative agent in a case of pseudohermaphroditism in a female. This clinical observation is supported by previously reported studies on the virilizing effect of aminoglutethimide on female rat fetuses. The various mechanisms by which this compound can cause virilization in the fetus are discussed.
LeMaire WJ, Cleveland WW, Bejar RL, Marsh JM, Fishman L. Aminoglutethimide: A Possible Cause of Pseudohermaphroditism in Females. Am J Dis Child. 1972;124(3):421-423. doi:10.1001/archpedi.1972.02110150119020