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March 1973

Antibiotic Treatment of Asymptomatic Bacteriuria

Author Affiliations

SP4, El Paso, Tex
From the departments of pediatrics (Dr. Scheinman) and medical research and development (Dr. Hester, Ms. Integlia, and Ms. Harvey), William Beaumont General Hospital, El Paso, Tex. Dr. Scheinman is now with the Department of Pediatrics, University of Minnesota, Minneapolis.

Am J Dis Child. 1973;125(3):349-352. doi:10.1001/archpedi.1973.04160030027005

Asymptomatic bacteriuria was detected in 27 (1.14%) of 1,389 girls utilizing an automatic urine collection seat with results confirmed by two additional clean-voided urine collections or by suprapubic bladder aspiration. Neither a microculture technique nor overnight refrigeration of specimens was found satisfactory for this program. Except for a suggestion of increased frequency of micturition, neither the clinical data obtained from parents nor the presence of proteinuria or pyuria were helpful in identifying girls with bacteriuria.

In a controlled trial of therapy, six to 12 month follow-up of 20 patients revealed a significant advantage of a brief course of antibiotic administration in eliminating bacteriuria (P =.02).