One hundred fifty children with impetigo were studied over a two-year period. Group A β-hemolytic streptococci were isolated from the skin lesions of the majority (75%) of patients. The streptococcal pyoderma strains were further classified by agglutination reactions with T-antisera, the most frequent patterns being 25/Imp.19, T-12, and 3/B3264. No predominant staphylococcal pyoderma strains were noted by phage typing.
Treatment with cleansing and local application of antibiotics were effective in healing the lesions within one to three weeks. Follow-up clinical examination and urinalyses revealed one patient who developed significant hematuria of acute glomerulonephritis, an attack rate of approximately 1%.
Hall WD, Blumberg RW, Moody MD. Studies in Children With ImpetigoBacteriology, Serology, and Incidence of Glomerulonephritis. Am J Dis Child. 1973;125(6):800–806. doi:10.1001/archpedi.1973.04160060014003