July 1973

Nutritional Supplementation in Treatment of Cystic Fibrosis of the Pancreas

Author Affiliations

Macclesfield, England
From the Macclesfield Hospital, Macclesfield, England.

Am J Dis Child. 1973;126(1):22-26. doi:10.1001/archpedi.1973.02110190018004

A nutritional supplement consisting of beef serum protein hydrolysate, a glucose polymer, and medium chain triglycerides was used to treat 17 patients with cystic fibrosis of the pancreas (CFP) for periods of 3 to 31 months. Increased rates of weight gain and linear growth were seen in seven of 11 patients for whom the supplement provided 100% of the recommended daily protein intake and 100% of the caloric needs.

Evaluation, using a clinical grading system, showed that there was marked improvement in general activity and in growth and nutrition, some improvement in pulmonary and physical findings, and no changes in the chest roentgenogram. Seven less severely affected patients who were given a 50% supplement showed less pronounced changes. The use of this nutritional supplement may improve the prognosis, and the management and life expectancy of patients with CFP.