We encountered four new cases of renal artery stenosis as the cause of hypertension in neurofibromatosis. A literature review documents the relationship between age and the probability of pheochromocytoma or renal artery stenosis as the cause of hypertension in neurofibromatosis. This review demonstrates that renal artery stenosis is seven times more likely than pheochromocytoma in such children. Renal arteriography is essential in the investigation of hypertension in children with neurofibromatosis.
Tilford DL, Kelsch RC. Renal Artery Stenosis in Childhood Neurofibromatosis. Am J Dis Child. 1973;126(5):665-668. doi:10.1001/archpedi.1973.02110190537016