The saliva of cystic fibrosis patients is known to have a high turbidity with an increased calcium level, which could predispose these patients to stone formation in their submandibular salivary glands. Twelve patients under 18 years of age suffering from sialolithiasis of the submandibular glands have been described since 1895 without proved or suggestive evidence of cystic fibrosis. This report gives the clinical, radiological, and pathological findings of a patient who had cystic fibrosis with sialolithiasis.
Bruns WT, Tang TT. Submandibular Sialolithiasis in a Cystic Fibrosis Patient. Am J Dis Child. 1973;126(5):685–686. doi:10.1001/archpedi.1973.02110190551019