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Article
December 1973

Systemic Lupus Erythematosus and Klinefelter Syndrome

Author Affiliations

Bridgeport, Conn
From the Department of Pediatrics (Dr. Landwirth) and Family Practice Medicine Program (Dr. Berger), Bridgeport Hospital, Bridgeport, Conn, and Yale University School of Medicine, New Haven, Conn.

Am J Dis Child. 1973;126(6):851-853. doi:10.1001/archpedi.1973.02110190693024
Abstract

A 13-year-old boy with Klinefelter syndrome who developed systemic lupus erythematosus is presented. To our knowledge, this is the fourth instance of this combination reported in the literature. The association of chromosomal anomalies and homologous autoantibodies in various clinical contexts may suggest an underlying relationship between these two phenomena.

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