March 1974

Recovery From Probable, Acquired Growth Hormone Deficiency

Author Affiliations

From the Department of Endocrinology, the Children's Hospital of Philadelphia, the University of Pennsylvania School of Medicine.

Am J Dis Child. 1974;127(3):397-399. doi:10.1001/archpedi.1974.02110220095013

A male patient developed almost complete growth arrest for three years following an acute febrile illness. There was no increase in serum growth hormone levels following insulin-induced hypoglycemia. His linear growth rate increased over a three-year period in response to human growth hormone therapy. At a later date, the patient was further treated with androgens, and had a normal pubertal growth spurt. He subsequently grew at a normal rate without therapy, achieving normal adult stature. Findings from growth hormone testing were now normal. It is postulated that this patient developed growth hormone insufficiency following his illness, and then recovered.