June 1974

Tetralogy of Fallot With Right Aortic Arch in Three Successive Generations

Author Affiliations

From the Pediatric Cardiovascular Center of Wisconsin, Milwaukee Children's Hospital; and the Department of Pediatrics, the Medical College of Wisconsin.

Am J Dis Child. 1974;127(6):877-878. doi:10.1001/archpedi.1974.02110250103016

A family had tetralogy of Fallot and right aortic arch in three successive generations. While the inheritance pattern of the cardiac lesion does not appear to follow classical mendelian genetics, genetic factors have certainly played a role in the familial aggregation of tetralogy in this family.