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July 1974

Angiomatous Lymphoid Hamartoma in an Infant

Author Affiliations

From the departments of surgery (general [Dr. Futrell] and pediatric [Dr. Izant]) and pathology (Dr. McKillop), Case-Western Reserve University School of Medicine, University Hospitals of Cleveland, Cleveland. Dr. Futrell is now with the Division of Plastic Surgery, the Johns Hopkins Hospital, Baltimore.

Am J Dis Child. 1974;128(1):96-99. doi:10.1001/archpedi.1974.02110260098020

To our knowledge, this is the first reported case of an angiomatous lymphoid hamartoma in an infant. Because of a histologic pattern similar to thymoma and because it has most often been found in the mediastinum, this unusual tumor has had a confusing clinical and pathologic history. The clinical course is usually benign and self-limiting although on occasion there is an associated iron-refractory anemia, hyperglobulinemia, and growth retardation. Resolution of these symptoms has been reported to occur following surgical excision of the lesion. Our patient was seen at age 4 months with a palpable axillary mass. Following surgical excision the child has remained asymptomatic for three years.