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October 1974

Sertoli Cell Tumor of Testis in Childhood

Author Affiliations

From the Laboratory Service, Veterans Administration Hospital, and the University of New Mexico School of Medicine, Albuquerque (Dr. Weitzner); and the Department of Pediatric Pathology, University of Bonn, West Germany (Dr. Gropp). Dr. Weitzner is now with the Veterans Administration Hospital, and the University of Texas, Health Science Center, San Antonio, Tex. Dr. Gropp is now with the Institut für Pathologie, Medizinische Hochschule Lübeck, West Germany.

Am J Dis Child. 1974;128(4):541-543. doi:10.1001/archpedi.1974.02110290111020

An 8-month-old boy who had a Sertoli cell tumor of the testis was alive and well 4½ years later. Review of the 23 patients with Sertoli cell tumor, including ours, showed 16 patients who were under 1 year of age. Two patients had a bilateral tumor. In another patient, it was located in an undescended testis. Sexual precocity occurred in one boy, and gynecomastia occurred in three boys, but regressed in two of them, following orchiectomy. Malignancy, as evidenced by retroperitoneal lymph node metastases, was present in only one boy. Since there are no clear-cut, gross or microscopical, pathological criteria to determine malignancy in this type of testicular tumor, careful follow-up is suggested.