December 1974

Necrotizing Arteritis

Author Affiliations

From the departments of pediatrics (Drs. Farooki and Green) and pathology (Dr. Brough), Wayne State University School of Medicine; and the departments of cardiology (Drs. Farooki and Green) and pathology (Dr. Brough), Children's Hospital of Michigan, Detroit.

Am J Dis Child. 1974;128(6):837-840. doi:10.1001/archpedi.1974.02110310085017

A 12-year-old boy with necrotizing arteritis developed massive pericardial effusion and cardiac tamponade. Eosinophilia of the blood and the pericardial fluid was striking. A pericardiectomy established the diagnosis of allergic granulomatous angiitis of Churg and Strauss. The pericarditis resolved, but it was followed by severe myocardial involvement, resulting in chronic congestive heart failure. The patient was treated with anticongestive, antiinflammatory, and immunosuppressive agents, but died 28 months after the onset of cardiac symptoms.