December 1974

Congenital and Neonatal Leukemia—Lymphocytic or Myelocytic?

Author Affiliations

From the departments of pediatrics (Drs. Wolk and Stuart) and pathology (Drs. Davey and Nelson), State University of New York, Upstate Medical Center, Syracuse, NY.

Am J Dis Child. 1974;128(6):864-866. doi:10.1001/archpedi.1974.02110310112022

To our knowledge, this is the first case of neonatal leukemia in which morphological and extensive cytochemical studies were performed. Although morphologically classifiable as myelogenous in cell type, cytochemical data defined this case as being lymphoblastic, as did the patient's response to chemotherapy. Both morphological and cytochemical studies should be performed on all future cases of congenital and neonatal leukemia, so that the origin of the cell types involved can be defined more precisely.